https://acrecanada.ca/events/3rd-acre-canada-meeting/
Conference Co-Chairs: Dr. Dake Qi (Pharmacy) and Dr. Garry Shen (Medicine), University of Manitoba
Local organizers: Dr. Jiming Kong (Anatomy and Cell Biology), Dr. Michael Czubryt (Physiology and Pathophysiology), and Dr. Sanjiv Dhingra (Physiology and Pathophysiology), University of Manitoba
Organizing Committee Members: Tianqing Peng and Qingping Feng (Western University), Ren-Ke Li and Burton Yang (U of Toronto), Dake Qi and Garry Shen (U of Manitoba), Guangdong Yang (Laurentian U), Dawei Zhang (U of Alberta), Ying Wang and Hong-Lin Luo (UBC), Xi-Long Zheng (U of Calgary), Wenbin Liang (U of Ottawa), Bernardo Trigatti (McMaster U).
7:30 – 9:00 AM Conference Registration, and Poster Setup
Breakfast
9:00 – 9:15 AM Opening Remarks
Dr. Dake Qi, University of Manitoba
Dr. Bernardo Trigatti, President of CSATVB, McMaster University
Dr. Qingping Feng, President of ACRE Canada, Western University
9:15 – 9:20 AM Dr. Jude Uzonna, Vice Dean of Research, Rady Faculty of Health Sciences, University of Manitoba
SESSION I: Cell functions and heart disease
Co-Chairs: Bernardo Trigatti and Dake Qi
9:20 – 9:40 PM Wnt signaling and cardiac remodeling: ion channels and beyond
Dr. Wenbin Liang, University of Ottawa, Ottawa, ON, Canada
9:40 – 10:00 PM Multiplex imaging of human coronary lesions defines the phenotype of macrophages with impaired phagocytic activity
Dr. Ying Wang, University of British Columbia, Vancouver, BC, Canada
10:00 – 10:20 PM BRD4 in vascular aging: Understanding the epigenetic control of smooth muscle function
Dr. Xi-Long Zheng, University of Calgary, Calgary, AB, Canada
10:20 – 10:40 PM Unraveling the mechanism of myocarditis: Viral manipulation of autophagy
Dr. Honglin Luo, University of British Columbia, Vancouver, BC, Canada
10:40 – 11:10 AM Refreshment Break and Trainee Poster Presentation
SESSION II: Development, Cardiac Injury and Regeneration
Co-Chairs: Wenbin Liang and Yaozu Xiang
11:10 – 11:30 AM Maternal environment in embryonic heart development: Role of eNOS
Dr. Qingping Feng, Western University, ON, Canada
11:30 – 11:50 AM Cardiac stem cell therapy: Still a long road to go
Dr. Sanjiv Dhingra, University of Manitoba, Winnipeg, MB, Canada
11:50 – 12:10 PM TBA
Dr. Bernardo Trigatti
12:10 – 12:30 PM Type-dependent differences in cardiovascular remodeling under mechanical overload: A comparative study
Dr. Jian Wu, Zhongshan Hospital, Fudan University, Shanghai, China
12:30 – 2:00 PM Box lunch and trainee poster presentation
SESSION III: Trainee Oral Presentations
Co-Chairs: Dawei Zhang and Ying Wang
2:00 – 2:15 PM TBA
2:15 – 2:30 PM TBA
2:30 – 2:45 PM TBA
2:45 – 3:00 PM TBA
3:00 – 3:15 PM TBA
3:15 – 4:00 PM Refreshment Break and Trainee Poster Presentation
SESSION IV: Keynote Presentation I
Chair: Dr. Ren-Ke Li
4:00 – 4:40 PM Circadian dependent regulation of cellular quality control mechanisms in the heart
Keynote Speaker: Dr. Lorrie Kirshenbaum, University of Manitoba, Institute of Cardiovascular Sciences, St. Boniface Hospital Albrechsen Research Centre, Winnipeg, MB, Canada
4:40 – 5:30 PM Trainee poster presentation
6:00 – 7:30 PM CSATVB and CAS member meeting, Room 800 JBRC (invited only)
SESSION V: Keynote Presentation II
Chair: Dr. Garry Shen
9:00 – 9:40 PM Shear stress and vascular inflammation
Keynote Speaker: Dr. Yu Huang, City University of Hong Kong, Hong Kong, China
SESSION VI: Trainee Oral Presentations
Co-Chairs: Guangdong Yang and Sanjiv Dhingra
9:40 – 9:55 AM TBA
9:55 – 10:10 AM TBA
10:10 – 10:25 AM TBA
10:25 – 10:40 AM Isovaleroylbinankadsurin A ameliorates atherosclerosis and restenosis by promoting LXRα and inhibiting TGF-β1 and FHL1 signaling pathways
Dr. Yaning Shi, PDF, Hunan University of Chinese Medicine, Changsha, China
10:40 – 11:10 AM Refreshment Break and Trainee Poster Presentation
SESSION VII: Smooth muscle and vascular diseases
Co-Chairs: Samantha Pauls and Heyu Ni
11:10 – 11:30 AM H2S regulation of iron homeostasis in smooth muscle cells
Dr. Guangdong Yang, Laurentian University, Sudbury, ON, Canada
11:30 – 11:50 AM Interplay of scleraxis and AngII regulates vascular smooth muscle phenotype and blood vessel structure
Dr. Michael Czubryt, University of Manitoba, Winnipeg, MB, Canada
11:50 – 12:10 PM Activation of endothelial Nrf2 prevents atherosclerosis in ApoE-/- mice by inhibiting inflammation and lipid peroxidation
Dr. Cheng-Lin Zhang, Shenzhen University Medical School, Shenzhen, China
12:10 – 12:30 PM Using PAR2 pathway-biased agonists to target specific endothelium-dependent vascular smooth muscle relaxation mechanisms in mouse arteries
Dr. John McGuire, Western University, London, ON, Canada
12:30 – 2:00 PM Box Lunch and Trainee Poster Presentation
SESSION VIII: Inflammation and metabolism
Co-Chairs: Michael Czubryt and Xi-Long Zheng
2:00 – 2:20 PM Impact of high nutrient loads and omega-3 fatty acids on monocyte metabolism and function
Dr. Samantha Pauls, University of Manitoba, Winnipeg, MB, Canada
2:20 – 2:40 PM HMOX1-LDHB interaction promotes ferroptosis by inducing mitochondrial dysfunction in foamy macrophages during advanced atherosclerosis
Dr. Jinwei Tian, Harbin Medical University, 2nd Affiliated Hospital, Harbin, China
2:40 – 3:00 PM Heart under stress: The impact of gestational diabetes on mitochondrial protein acetylation
Dr. Vernon Dolinsky, University of Manitoba, Winnipeg, MB, Canada
3:00 – 3:20 PM Gut hormones in the regulation of intestinal lipids
Dr. Changting Xiao, University of Saskatchewan, SK, Canada
3:20 – 4:00 PM Refreshment Break and Trainee Poster Presentation
SESSION IX: Potential therapeutic strategies for cardiac diseases
Co-Chairs: Honglin Luo and Qingping Feng
4:00 – 4:20 PM Strategies for rebalancing hematopoiesis against myocardial infarction and heart failure
Dr. Yaozu Xiang, Tongji University, Shanghai, China
4:20 – 4:40 PM STAT3 signaling in conditioning cardioprotection in normal and functionally impaired heart
Dr. Zhengyuan Xia, University of Hong Kong, Hong Kong, China
4:40 – 5:00 PM TBA
TBA
5:00 – 5:20 PM Consideration of Perioperative management of end-stage heart disease: from evidence-based medicine to clinical practice
Dr. Sheng Wang, Anding Hospital, Capital Medical University, Beijing, China
5:20 – 6:00 PM Trainee Poster Presentation
6:00 – 9:00 PM Conference dinner
SESSION X: Gary Lopaschuk Memorial Lecture
Chair: Vernon Delinsky
9:00 – 9:50 AM The Role of Pyruvate Dehydrogenase & Glucose Oxidation in Cardiovascular Disease: A Tribute to Dr. Gary Lopaschuk
Dr. John Ussher, University of Alberta, Edmonton, Canada
9:50 – 10:30 AM Refreshments break and Trainee Poster Presentation
SESSION XI: Potential therapeutic strategies for vascular diseases
Co-Chairs: Changting Xiao and Zhengyuan Xia
10:30 – 10:50 AM Control of Heart Attack and Stroke – developing novel anti-platelet therapy against atherothrombosis
Dr. Heyu Ni, University of Toronto, ON, Canada
10:50 – 11:10 AM Anti-atherosclerotic effect and mechanism of Tripterygium wilfordii
Dr. Li Qin, Hunan University of Traditional Medicine, Changsha, China
11:10 – 11:30 AM Vascular protection in atherosclerosis: unveiling the potential of traditional Chinese medicine
Dr. Guanwei Fan, Tianjin University of Traditional Chinese Medicine, Tianjin, China
11:30 – 11:50 AM The influence of Saskatoon berry intake on metabolism and vascular function in healthy humans: relationship with gut microbiota and short chain fatty acids
Dr. Garry Shen, University of Manitoba, Winnipeg, MB, Canada
11:50 – 12:20 PM Trainee Presentation Award Ceremony
Group Photo of Awardees
12:20 – 12:30 PM Closing Remarks
Dr. Gary Shen, Conference Co-Chair, University of Manitoba
Dr. Ren-Ke Li, President-Elect, ACRE Canada
12:30 – 1:30 PM Lunch
1:30 – 2:30 PM ACRE Canada business meeting
2:30 PM Conference ends